MitoLife NAD Power

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DO YOU WANT MORE ENERGY?

While vitamin B12 tends to get the spotlight, vitamin B3 is often overlooked. It is a nutrient critical for proper mitochondrial energy production and basic metabolic processes. If it is contained in a multi-vitamin, it is under-dosed while other nutrients best acquired from food are over-dosed.

If one is talking vitamin B3, it is usually a harmful form called niacin to induce a "flush". Usually niacin is combined with far infrared sauna sweating and rebounding on a trampoline. This is supposed to be anti-aging. Unfortunately this is very detrimental to health. There is a huge release of serotonin (a stress hormone) and prostaglandin D2 (an inflammatory marker) when high dose niacin (flushing or non-flushing) is ingested (Papaliodis, et al, 2008). This is an extreme stress to the body and will lower the metabolic rate.

A much safer alternative to niacin is niacinamide, sometimes referred to as nicotinamide. Niacinamide is a precursor of nicotinamide adenine dinucleotide (NAD+) and is involved in a multitude of intra- and inter-cellular processes, which regulate some of the cell's metabolic, stress, and immune responses to physiological or pathological signals.

Niacinamide is readily converted into the active forms of niacin: NAD+, NADH and NADPH, which are co-factors in cellular energy production, help to maintain DNA stability, and allow over 200 enzymatic reactions to take place.

NAD stands for nicotinamide adenine dinucleotide, which is a key enzyme that allows the production of adenosine triphosphate, or ATP, cellular energy. Niaacinamide has been investigated for potential neuroprotective effects in cellular, animal, and human studies (Rennie, et al., 2015).

BENEFITS:

Increases mitochondrial energy production*
Neuroprotective
Reduces pigmentation, wrinkles and sebum production
Acts as an antioxidant
Suppresses SIRT2 gene, which may extend lifespan*
Protects against ultraviolet-induced skin damage and immune suppression*
Suppresses the SIRT1 gene* (Ref)
Inhibits the release of free fatty acids* (Ref) (which may improve glucose utilization*)
Decreases prostaglandin synthesis* (Ref)
Inhibits nitric oxide*
Reduces serotonin synthesis*
Protects the pancreas, nerves, vascular cells*
Increases metabolic rate*